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POEM ON DIABETES

  Diabetes, oh silent thief, Stealing away our health like a leaf, In the wind, it blows away, Leaving us struggling to find a way. High blood sugar, our constant foe, Making us tired and feeling low, Thirsty and hungry all the time, Wondering if we'll ever be fine. Insulin, the hormone we need, To help our bodies properly feed, But when it's lacking, trouble brews, And diabetes becomes the news. Type 1, Type 2, gestational too, Diabetes comes in different hues, But one thing is clear, it's no friend, And can cause our health to swiftly end. So let's take care of ourselves each day, Watch what we eat and what we say, Stay active, and take our meds, And keep diabetes from taking the lead. With proper care, we can thrive, Live life to the fullest and stay alive, Diabetes may be a part of our life, But it doesn't have to cause us strife.

Short notes in pharmacology

 Paper1 An inverse agonist is a type of ligand that binds to a receptor and causes an opposite effect to the endogenous agonist, resulting in a decrease in basal activity of the receptor. Here is a detailed pointwise description of an inverse agonist: 1.      Receptor activation: Receptors are proteins located on the cell membrane or inside the cell that bind to specific ligands such as neurotransmitters, hormones, or drugs. When an agonist binds to a receptor, it activates the receptor and initiates a signal transduction pathway that leads to a cellular response. 2.      Basal activity: Basal activity is the level of activity of a receptor in the absence of any ligand. Receptors can have a basal level of activity even when no agonist is present, due to their inherent activity or due to ligand-independent activation. 3.      Inverse agonist binding: An inverse agonist is a ligand that binds to a receptor and causes a decrease in basal activity, resulting in an opposite ef